Antiproliferation effect of the uremic toxin para-cresol on endothelial progenitor cells is related to its antioxidant activity

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Antiproliferation effect of the uremic toxin para-cresol on endothelial progenitor cells is related to its antioxidant activity

Endothelial dysfunction and impaired endothelial regenerative capacity are key contributors to the high incidence of cardiovascular disease in patients with chronic kidney disease (CKD). Uremic toxins are associated with this pathogenesis. Previous studies have revealed that a uremic toxin, para‑cresol (p‑cresol), exerts an antiproliferation effect on human endothelial progenitor cells (EPCs), ...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2017

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2017.6230